Can Intel GMA 4500M play Transformers 2 PC?

The problem is your Graphics card, it's not good enough to run the game. If you want to try to make it run a bit less laggy/blurry, try closing ALL background programs that you have running in the background such as messengers, Limewire and other P2P programs, and any other programs you aren't using at the moment. That's pretty much all you can do to make it run less laggy.